Saccadous, Inc. is a startup dedicated to providing the world’s best non-invasive platform (hardware, software and analytics) for diagnosing, tracking and advancing the treatment of neurological diseases and disorders such as Traumatic Brain Injury (TBI).
This is done through the capture and analysis of eye-movements at the microsaccade level or "fixational eye-movements". During visual fixation, the eyes are never completely still, but produce small involuntary movements, called “fixational eye movements,” including microsaccades, drift, and tremor. The research and intellectual property we have licensed has proven that microsaccade attributes such as magnitudes, velocities, durations, and intervals when compared show patterns that can be used to identify and differentiate subjects.
FDA DISCLAIMER: The products, technology, programs, articles and/or any other media, presented on the Saccadous website have not been evaluated by the Food and Drug Administration (FDA). This test is currently not available to the general public. If you are interested in learning more about the past and ongoing research behind Saccadous, email us.
The Saccadous solution (mobile, cloud-based & non-invasive) adds involuntary eye movements as a new evidence-based data source which we believe directly aligns with an aggressive and on ongoing Healthcare and Life Sciences transformation – the digital age in which mobile technologies, sensors, and advances in analytics make it possible to capture and decipher vast amounts of information.
- Non-invasive – Subjects are only required to fixate on a mobile device screen for several periods of around 30 seconds each
- Mobile - We have been able to move this capability out of the lab onto a mobile device
- Inexpensive – Our infrastructure is cloud-based, scalable and globally accessible
- Digital – The Saccadous solution (mobile, cloud-based & non-invasive) adds involuntary eye movements as a new evidence-based data source which we believe directly aligns with an aggressive and on ongoing Healthcare and Life Sciences transformation – the digital age in which mobile technologies, sensors, and advances in analytics make it possible to capture and decipher vast amounts of information.
>> Watch our video here.
Saccadous has licensed the following Intellectual Property (IP) from Dignity Health/Barrow Neurological Institute:
(App. Serial No. (Country Code) and TITLE):
- 2814236 (CA) -- EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION
- 2704777 (CA) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 2827498 (CA) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 9850659.5 (EP) -- EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION
- 12739478.1 (EP) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 61/986,032 (US) -- SYSTEMS & METHODS FOR USING EYE MOVEMENTS TO DETERMINE STATES
- 60/968,238 (US) -- MICROSACCADIC INDICATORS OF COVERT ATTENTIONAL FOCI
- 60/984,628 (US) -- OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSP PATIENTS & HEALTHY VOLUNTEERS
- 12/199,625 (US) -- EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION
- 12/740,008 (US) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 61/437,138 (US) -- OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSP PATIENTS & HEALTHY VOLUNTEERS
- 13/359,828 (US) -- OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSP PATIENTS & HEALTHY VOLUNTEERS
- 14/220,265 (US) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 62/040,166 (US) -- SYSTEMS AND METHODS FOR USING EYE MOVEMENTS TO DETERMINE TRAUMATIC BRAIN INJURY
- US2009/061330 (PCT) -- EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTN
- US2008/082034 (PCT) -- METHOD OF DETECTING NEUROLOGICAL DISEASE
- 8,668,337 (US) -- SYSTEM FOR PHYSIOLOGICAL EVALUATION OF BRAIN FUNCTION
- 9,101,312 (US) -- SYSTEM FOR PHYSIOLOGICAL EVALUATION OF BRAIN FUNCTION
There are currently no significant medical physiological diagnostics for neurological disease and traumatic brain injury. These assessments are opinions made by medical doctors based on behaviors exhibited by the patient. The brain controls every part of the human body. By using high speed cameras, researchers at Barrow Neurological Institute in Phoenix have discovered that the way the human eye drifts and corrects (square-wave jerks) to maintain focus, can reveal certain ailments affecting the brain.
We see the following commercial applications for this product: (1) Diagnostic Tool for Physicians (2) Tool for Clinical Research in the Pharma/CROs space for things like: Clinical Trials, Drug Effectiveness, Patient Recruitment (3) Other applications TBI – Traumatic Brain Injury Detection, Measuring Fatigue, Drug Use Detection and (4) Future Vision includes: Patient Self-Service (CVS, Walgreens), API Accessible Platform (Mobile Applications).
This technology has the potential to diagnose and differentiate neurological disease at a very early stage. When symptoms begin to present, doctors will be able to track the microsaccades and match the velocity and magnitude of the drift and correction with those of other known disease patients. For example, microsaccade direction for Alzheimers disease presents as increased vertical eye movement, whereas Parkinsons patients present in a diagonal pattern. Similarly, athletes engaged in competitive athletics will be able to record baseline eye movement patterns prior to the season, and then eye movements can be measured throughout the season and/or post-injury to confirm the concussion. The ability to diagnose a concussion on the sideline of a football field on a Friday night in near-real-time will be a game-changer.