Research

Our technology and patented IP is based simply on the premise that eye movements of people with neurological disease differ significantly from healthy people. This conclusion is based on 10+ years of research from our inventors Dr. Stephen L. Macknik and Dr. Susana Martinez-Conde. Some of their published research is listed below with a URL link to the published work:

1. Distinctive features of microsaccades in Alzheimer’s disease and in mild cognitive impairment (Kapoula Z, Yang Q, Otero-Millan J, Xiao S, Macknik SL, Lang A, Erny M, Martinez-Conde S (2014) AGE; 36(2), 535-543)

2. Distinctive features of saccadic intrusions and microsaccades in progressive supranuclear palsy (OteroMillan J, Serra A, Leigh RJ , Troncoso XG, Macknik SL, Martinez-Conde S (2011) Journal of Neuroscience; 31(12): 4379-4387)

3. Saccades during attempted fixation in parkinsonian disorders and recessive ataxia: From microsaccades to square-wave jerks (Otero-Millan J, Schneider R, Leigh RJ, Macknik SL, Martinez-Conde S (2013) PLOS ONE)

4. The impact of microsaccades on vision: towards a unified theory of saccadic function (Martinez-Conde S, Otero-Millan J, Macknik SL (2013) Reviews Neuroscience; 14, 83-96)

5. Microsaccades: a neurophysiological analysis (Martinez-Conde S, Macknik SL, Troncoso XG & Hubel DH(2009) Neurosciences; 32, 463-475)

6. The Disturbance of Gaze in Progressive Supranuclear Palsy (PSP): Implications for Pathogenesis (Chen AL, Riley DE, King SA, Joshi AC, Serra A, Liao K, Cohen ML, Otero-Millan J, Martinez-Conde S, Strupp M, Leigh RJ (2010) Frontiers in Neuro-otology, 1:147)

More Eye Movement Research: http://smc.neuralcorrelate.com/publications/  http://macknik.neuralcorrelate.com/publications/  Some other (non-Saccadous) research: Eye Test May Diagnose ADHD, Predict Treatment Response - Monitoring Eye Movements May Aid in Psychiatric Diagnosis, Treatment - Increased microsaccade rate in individuals with ADHD

 

Intellectual Property (IP) - Inventory of Patents with Exclusive Licensing Rights

2814236 (CA) EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION

2704777 (CA) METHOD OF DETECTING NEUROLOGICAL DISEASE

2827498 (CA) METHOD OF DETECTING NEUROLOGICAL DISEASE

9850659.5 (EP) EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION

12739478.1 (EP) METHOD OF DETECTING NEUROLOGICAL DISEASE

61/986,032 (US) SYSTEMS METHODS FOR USING EYE MOVEMENTS TO DETERMINE STATES

60/968,238 (US) MICROSACCADIC INDICATORS OF COVERT ATTENTIONAL FOCI

60/984,628 (US) OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSPALSY PATIENTS & HEALTHY VOLUNTEERS

12/199,625 (US) EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTENTION

12/740,008 (US) METHOD OF DETECTING NEUROLOGICAL DISEASE

61/437,138 (US) OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSP PATIENTS & HEALTHY VOLUNTEERS

13/359,828 (US) OBJECTIVE CHARACTERIZATION OF SQUARE-WAVE JERKS IN PSP PATIENTS & HEALTHY VOLUNTEERS

14/220,265 (US) METHOD OF DETECTING NEUROLOGICAL DISEASE

62/040,166 (US) SYSTEMS AND METHODS FOR USING EYE MOVEMENTS TO DETERMINE TRAUMATIC BRAIN INJURY

US2009/061330 (PCT) EYE MOVEMENTS AS A WAY TO DETERMINE FOCI OF COVERT ATTN

US2008/082034 (PCT) METHOD OF DETECTING NEUROLOGICAL DISEASE

US2012/022959 (PCT) METHOD OF DETECTING NEUROLOGICAL DISEASE

US 8,668,337 B2 SYSTEM FOR THE PHYSIOLOGICAL EVALUATION OF BRAIN FUNCTION

US 9,101,312 B2 SYSTEM FOR THE PHYSIOLOGICAL EVALUATION OF BRAIN FUNCTION – CONTINUATION